Very Reasonable: I just did it with Level 188 4/2/3 without any boosts. First try.
Championed HB blasted this with one punch
First try with the champed Hulkbuster…although the board was quite unfriendly. Lost about half of his health before firing off a 20 AP Repulsor Punch.
Token was a green Gwenpoole, putting her at 1/0/4. Why is Gwenpoole still in the token rotation, but Devil Dinosaur and Howard the Duck aren’t?
Took 5 tries but my 3/1/2 LVL 131 HB did it, had to use 
/ 
+2, stockpile +2, damage boost + 100%. Got 
bringing him to 3/2/2
It took 5 tries (2 due to game crashes), but Hulkbuster got the job done. The Legendary token gave a 
(it seems this round gave a lot of people Natasha), so she’s now 1/1/2–my best 5*. Not too shabby…
Champed at 282, got Hulk on the first try without boosts, although the game took a while because of a lack of red on the board.
Got a red Medusa.
5/2/4 level 135 Lost
Leveled Him up to 144 and eeked out a win
Got my first 5 Star Thanos Cover (green)
4/2/5 HB at lvl 146 got it done first try. Used AP boosts just to be safe, not sure if needed.
Definitely prioritized blue surprisingly, then red. That made a lot of green on the board go bye bye.
Of course the only Clap he got on me took out both of my Overdrive strike tiles, but I soon got to 30 red aaaaand punch.
Will open the LT tomorrow.
Got it first try with my 3/1/3 131 with +2r+y/+2 all and r+y 50% boost.
Had a very green/red lite board, saved 30 Red, hit and built up red again to beat him.
Got a XFWolvie to add champ level.
Champ IMHB handled it first try without boosts. He did get me to about 1/3 health, but a 
followed by a
handled it.
Forgot to post this yesterday but I managed to barely win with my 1/5/1 level 156 (maximum).
With only one red cover, you’re doing a measly 3500 damage with 30 AP (and triggering Anger); additionally, using my best power (black) lopped off more than 10% of my health pool.
I used +2 black AP and then +20% r/y and g/b match damage boosts - I did not want to go higher because damage boost+strike tile damage has the potential to trigger Anger on every match.
I think I had to try 4 times. On the winning run, I got strike tiles out early and was able to strongly deny red and green. My match damage with strike tiles stayed under the Anger threshold.
I think he maybe got one green off, but I just kept whittling him down until I could finally finish him with my red (I had maybe 800 health remaining).
Reward was 
, he is 3/3/3 which is nice.