At this point, once your main planeswalker is injured and you cannot progress the story, there doesn’t seem to be any point in farming anything except the first level.
All of them give 50 runes and nothing else.
What I’m wondering is why that is the case?
same with MPQ - all PVE nodes give you 20 ISO after you get all rewards. Nothing new here=)
Somewhat true I suppose, we really need events and repeatable grind.
With PvP being mostly pointless there doesn’t seem to be a good way to get runes right now.
We can’t even sell cards!
The game got a full release less than 24 hours ago, got to be a little patient right now, haha.
“Full release” implies a full game. This feels very unfinished at this point. Campaign is alright, but is that what they want to use to get us hooked? I’d expect a day one event even if it were minor and some sort of reward structure for pvp system.
Events are coming, and we have plans for duplicate spells. I wouldn’t recommend getting rid of them even if you could sell them. 
“Coming” like scheduled, or still being tweaked?
Any comments on leader board rewards?
Current plan is 1.3.0 for both those features (Leaderboard rewards and Events in general). I don’t have a release date with 1.3.0 yet. It’s in heavy development at the moment, and with the holidays around the corner, things could move.