This happened twice when cycling Vizier of Tumbling Sands. The cycling animation didn’t complete, with the first card in hand being a blank space. This stops game play, with the player unable to rearrange cards in hand or match gems, forcing one to terminate the game.
Both times, this occurred the turn after an effect disabled one of my creatures–once Emrakul, once Ajani Vengeant’s first ability.
Outside of these two instances, the cycling for this card works fine.
No comment on if the spell can be cast, because who ever casts Vizier of Tumbling Sands?