I noticed that for all 3-star heroes, the displayed cost to level a particular hero would increase as I gain ISO-8 in bank.
For example, say that my ISO-8 bank is empty. The displayed cost to level my Doctor Doom to level 166 would be around 76,000. I would play a bit to get about 6,000 ISO-8 in the bank. I would recheck the cost to max out Doctor Doom, and the cost has now increased to 80,000.
This has happenned to all 3-star heroes for a few months now.
This does not occur with 2-star heroes.