I’ve been working my way through my 4*'s and champing them. I’ve managed to champ 45 of them and I have another 26 that have enough covers but need more ISO-8. The problem is I’m not sure which ones I should prioritize right now.
The characters in question are:
Jubilee
War Machine
Sam Wilson
Ghost
Quake
X-23
Ghost Rider
Mr. Fantastic
Nebula
Spider-Woman
The Hulk (Totally Awesome)
Venom
Kingpin
The Thing
Spider-Man
Ant-Man
Lockjaw
Namor
Mordo
Gwenpool
Wasp
Karolina Dean
Super-Skrull
Ronin
Sandman
Maria Hill
Any suggestions for which I should champ first or which I should leave would be great.
All of these are only useful when boosted or in special situations (Quake/Wasp). Otherwise you almost surely have better options given you have 45 already champed.
Quake is very handy in Shield Sim vs Juggs/Grocket/Gamora teams (pair her with your Juggs/Grocket and target enemy Gamora 1st).
Wasps Black stun is very handy esp when the damage component is triggered and the Blue is annoying (and works well with Carol + Grocket in shield sim teams since it expires every turn triggering Carols boost).
Ghost is a beast when boosted with her 5* match damage.
Mordo’s Purple is devastating vs teams that can’t use one of their colors (primary is a passive) and his Blue hits like a truck.
Gwenpools Purple is a unique power due to targeted destruction of row/column and her Green hits hard.
Spiderman may also be worthy of champing if you also have the other 4* spider characters (SpiderGwen, 2099, Miles) champed since they can form a super synergy team of web tile awesomeness that can take down high level teams (L400 plus)
I would also say that whilst Ghost is pretty good, I find that I don’t really use her as I have Karnak champed and he is far more devastating.
X-23 is worth considering because she is normally an Essential in X-Men v Apocalypse (assuming we will get more Boss Battles).