I just started using Dr Strange. I used his purple power for first time in current PVE. Enemy Daken had 2 strike tiles on the board. Dr Strange Eye of Agamotto would just pulse then do nothing.
Screenshot of the power being out:
http://imgur.com/a/9n58X
Next turn:
http://imgur.com/a/a7iD5
Next Turn:
http://imgur.com/a/iReYU
Next turn: (matched another green)
http://imgur.com/a/MA2Tr